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Preservation of Pharmaceutical Products Using Antimicrobial Agents
  • Health Science

Preservation of Pharmaceutical Products Using Antimicrobial Agents

March 27, 2023
by Santhakumar Raja
3 min read
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Antimicrobial preservatives are added to non-sterile dosage forms to protect them from microbial growth or from microorganisms that are introduced inadvertently during or after the manufacturing process. Antimicrobial...

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Assessment of Microbial Contamination and Spoilage
  • Health Science

Assessment of Microbial Contamination and Spoilage

March 25, 2023
by Santhakumar Raja
2 min read
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Microbial contamination and spoilage are assessed by the following methods: Physical and Chemical Changes: Microbial contamination and spoilage in various pharmaceutical formulations can be identified by the physical and...

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Standardisation of Amino Acids
  • Health Science

Standardisation of Amino Acids – theteche.com

March 21, 2023
by Santhakumar Raja
2 min read
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Microbiological assays were used for quantitation of amino acids since many years as they were the most reliable, and specific available tests. They can be used for any type of biological material; however sometimes they are...

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Cavities Prepared in Sterile Agar Medium for Assay of Antibiotics
  • Health Science

Cup-Plate or Cylinder-Plate Method

March 18, 2023
by Santhakumar Raja
4 min read
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This method relies on the diffusion of an antibiotic from a vertical cavity or a cylinder 2 through the solidified agar layer in a petri plate. The growth of test microorganisms is observed to be inhibited in a circular area or...

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Microbiological Assay by Tube Assay Method
  • Health Science

Turbidimetric or Tube Assay Method

March 18, 2023
by Santhakumar Raja
2 min read
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This method depends on the microbial culture growth in a uniform solution of antibiotic in a fluid medium favourable to its rapid growth in the absence of antibiotic. This method involves a shorter incubation period (4-5 hours)...

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Curve of Diameter of Zone of Inhibition versus Log Concentration of Antibiotics
  • Health Science

Methods for Standardisation of Antibiotics

March 18, 2023
by Santhakumar Raja
3 min read
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Antibiotics are the agents that kill or reduce the bacterial growth. They belong to a class of antimicrobials (a larger group also comprising of anti-viral, anti-fungal, and anti- . parasitic drugs). Antibiotics are chemicals...

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Methods of Prevention of Contamination
  • Health Science

Methods of Prevention of Contamination – theteche.com

March 16, 2023
by Santhakumar Raja
4 min read
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The steps by which microbial contamination of products can be prevented in aseptic areas are discussed below: Personnel : They can take the following measures: Access to production areas by the unauthorised personnel should be...

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Different Sources of Contamination in an Aseptic Area
  • Health Science

Different Sources of Contamination in an Aseptic Area

March 16, 2023
by Santhakumar Raja
3 min read
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There are various contamination sources in an aseptic area, which are discussed below: Personnel : Those supervising, performing, or controlling drug manufacturing are a potential source of microbial contamination, due to the...

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Vertical Laminar Airflow Hood
  • Health Science

Types of Laminar Airflow Hood – theteche.com

March 15, 2023
by Santhakumar Raja
2 min read
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A laminar airflow hood is of two types: Horizontal Airflow Hoods These hoods (figure) sweep the filtered air from the back to the front of the hood. An electrical blower draws the contaminated room air using a pre-filter (similar...

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Laminar Airflow Hood
  • Health Science

Laminar Flow Equipment (Laminar Airflow Hood)

March 15, 2023
by Santhakumar Raja
3 min read
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A Laminar Airflow Hood (LAFH)/ Laminar Aseptic Hoods, or a workbench, is a primary engineering control device which provides the following services during aseptic compounding: Clean air to the critical sites (immediate aseptic...

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Recent Posts

  • Preservation of Pharmaceutical Products Using Antimicrobial Agents
  • Assessment of Microbial Contamination and Spoilage
  • Standardisation of Amino Acids – theteche.com
  • Cup-Plate or Cylinder-Plate Method
  • Turbidimetric or Tube Assay Method
  • Methods for Standardisation of Antibiotics
  • Methods of Prevention of Contamination – theteche.com
  • Different Sources of Contamination in an Aseptic Area
  • Types of Laminar Airflow Hood – theteche.com
  • Laminar Flow Equipment (Laminar Airflow Hood)
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