These receptors belong to a large family of cell membrane receptors. These receptors are bonded with effector (enzyme/channel/carrier protein) by one or more GTO-activated protein (G-protein) to give effective response. The...
The drug receptor interaction may be affected by : Isosterism : Isosteres are groups of atoms having identical physical or chemical properties of a molecule due to resemblance in size, electronegativity, or stereochemistry, and...
In molecular terms, the activity of drugs is initiated by their atomic level interaction with a receptor. Since the association of small molecules (e.g., drugs) with macromolecules (e.g., receptors) is promoted and stabilised by...
Drugs can bind either through plasma proteins or blood cells : Binding of Drugs to Plasma Proteins : In systemic circulation drug interacts with plasma and blood components (plasma proteins, blood cells and haemoglobin). In blood...
Drugs distribution is affected by : Age : Distribution varies with difference in : Total Body Content (Intracellular and Extracellular) : It is maximum in infants. Fat Content : Greater in infants and in elder ones. Skeletal...
A number of drugs are yielded by plants and animals. This classification can be done according to the physical and chemical properties of the drug. In this, drugs are categorised in the following groups: Alkaloids : Compounds...
The following points help to understand the nature of drugs in a better manner: Physical State of Drug : At room temperature, drugs may either be in the form of solid (e.g., aspirin, atropine), liquids (e.g., nicotine, ethanol)...
Introduction of Drugs In general, any substance which brings about a change in the biological functions by way of its chemical action is defined as a drug. Drug may be a therapeutic agent which is used in the prevention...
Introduction to Pharmacology Pharmacology is the study of various characteristics of drug molecules and related compounds. The term Pharmacology originated from Greek words Pharmacon (meaning drug.) Logos (studied in, i.e...
We first discuss distance vector routing. This method sees an AS, with all routers and networks, as a graph, a set of nodes and lines (edges) connecting the nodes. A router can normally be represented by a node and a network by a...
